Addendum to: Nature https://doi.org/10.1038/nature03124 Published online 18 November 2004

The Editors would like to alert the readers to concerns raised regarding some of the microscopy images presented in this article, specifically:

Figure 1g: VSV Untreated and + Anti-IFN-α neutralising Ab images appear to overlap;

Figure 4a: Wild type –IFN, IKKβ–/– –IFN, Fig. 4g VSV Irf3–/– and VSV + IFN-α/β pre-treatment images appear to originate from the same sample;

Figure 4a: IKKα–/– –IFN and Fig. 4g VSV Irf3+/+ images appear to overlap;

Figure S1a: MOCK FADD+/–, FADD–/– and Fig. S1c MOCK FADD+/– images appear to originate from the same sample;

Figure S2a: VSV Casp8+/+ and Casp8–/– images appear to overlap.

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Author notes- These authors contributed equally: Siddharth Balachandran, Emmanuel Thomas

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- Department of Microbiology and Immunology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA

Siddharth Balachandran, Emmanuel Thomas & Glen N. Barber

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Balachandran, S., Thomas, E. & Barber, G.N. Editorial Expression of Concern: A FADD-dependent innate immune mechanism in mammalian cells.

Nature (2026). https://doi.org/10.1038/s41586-026-10397-8

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- Published: 19 March 2026

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- DOI: https://doi.org/10.1038/s41586-026-10397-8

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