Bacterial−viral conflicts shape cholera evolution
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Cholera, an intense dehydrating diarrhoeal disease, is one of the worst infections that afflict parts of the world lacking access to safe drinking water. Pandemics are not limited to respiratory infections, and the world is currently in the seventh pandemic of cholera, which started in the early 1960s and is caused by a bacterial infection of the gut. In parts of South Asia, cholera is endemic (continually present), and India and Bangladesh — the Ganges River delta and basin region in particular — have long been considered launchpads for global spread1. The natural predators of the bacterium that causes cholera (Vibrio cholerae) include viruses called bacteriophages or phages. There is interest in understanding the extent to which such interactions influence cholera epidemiology and evolution in this seventh pandemic. Writing in Nature, Barton et al.2 and Mathur et al.3 present such analyses.
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Nature 653, 356-357 (2026)
doi: https://doi.org/10.1038/d41586-026-01156-w
References
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Competing Interests
The authors declare no competing interests.
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