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Subjects

- Diabetes

- Drug discovery

- Obesity

The Original Article was published on 29 April 2026

Correction to: Nature https://doi.org/10.1038/s41586-026-10427-5 Published online 29 April 2026

In the version of this article initially published, there were errors in the Fig. 4d colour key labels, where the label now reading “GLP-1-GIP–Lani” alongside the red filled circle originally indicated “GLP-1”, while the label now reading “GLP-1–Lani” alongside the white open circle was originally written “GLP-1-GIP–Lani”. The figure is now amended in the HTML and PDF versions of the article.

Author information

Author notes- These authors contributed equally: Daniela Liskiewicz, Aaron Novikoff

Authors and Affiliations

- Institute for Diabetes and Obesity, Helmholtz, Munich, Germany

Daniela Liskiewicz, Aaron Novikoff, Ahmed Khalil, Seun Akindehin, Russell L. Castelino, Callum Coupland, Cristina Garcia-Caceres, Gerald Grandl, Robert M. Gutgesell, Daniel T. Haas, Ezgi Karaoglu, Pamela Kakimoto, Arkadiusz Liskiewicz, Xue Liu, Gandhari Maity-Kumar, Paul T. Pfluger, Sneha Prakash, Alberto Cebrian-Serrano, Natalie Krahmer & Timo D. Müller

- German Center for Diabetes Research (DZD), Munich, Germany

- Institute of Physiotherapy and Health Sciences, Academy of Physical Education, Katowice, Poland

Daniela Liskiewicz

- Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA

Jonathan E. Campbell

- Duke Molecular Physiology Institute, Department of Medicine, Division of Endocrinology, Duke University, Durham, NC, USA

Jonathan E. Campbell, Danielle C. Leander & Marshall Paisley

- UR 2465, Laboratoire de la Barrière Hémato-Encéphalique (LBHE), Université Artois, Lens, France

Pietra Candela, Maxime Culot & Fabien Gosselet

- Indiana Biosciences Research Institute, Indianapolis, IN, USA

W. Scott Dodson, Jonathan D. Douros, Stephanie A. Mowery & Patrick J. Knerr

- Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA

Jonathan D. Douros, Brian Finan, Stephanie A. Mowery & Patrick J. Knerr

- Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Hannes Embring, Patricia S. S. Petersen & Zachary Gerhart-Hines

- Core Facility Pathology and Tissue Analytics, Helmholtz, Munich, Germany

Annette Feuchtinger & Monica Tost

- Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Munich, Germany

Cristina Garcia-Caceres

- Department of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA

Xiao-Bing Gao, Junichi Yoshida & Tamas L. Horvath

- Institute of Computational Biology, Helmholtz Munich, Munich, Germany

Robert M. Gutgesell

- Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden

Martin Jastroch & Michaela Keuper

- Department of Pharmacology, Experimental Therapy and Toxicology, Institute for Experimental and Clinical Pharmacology and Pharmacogenomic, Eberhard Karls University, Interfaculty Center of Pharmacogenomic and Drug Research, Tübingen, Germany

Ezgi Karaoglu

- Institute for Cardiovascular Prevention (IPEK), University Hospital, LMU Munich, Munich, Germany

Anna Cristina Kaltenbach, Sabine Steffens & Christian Weber

- Touchstone Diabetes Center, The University of Texas Southwestern Medical Center, Dallas, TX, USA

Christine M. Kusminski & Philipp E. Scherer

- Department of Physiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice, Poland

Arkadiusz Liskiewicz

- CIMUS, University of Santiago de Compostela, Instituto de Investigación Sanitaria, Santiago de Compostela, Spain

Sara Martinez Martinez & Ruben Nogueiras

- Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA

Diego Perez-Tilve

- Research Unit Neurobiology of Diabetes, Helmholtz Munich, Neuherberg, Germany

Paul T. Pfluger

- Division of NeuroBiology of Diabetes, TUM School of Medicine and Health, Technical University Munich, Munich, Germany

Paul T. Pfluger

- Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center (HDC), Helmholtz Zentrum München (Helmholtz Munich), Munich, Germany

Sabine Steffens

- DZHK (German Centre for Cardiovascular Research) Partner Site, Munich Heart Alliance, Munich, Germany

Sabine Steffens & Christian Weber

- Department of Surgery, University of Michigan, Ann Arbor, MI, USA

Jordan Wean & Randy J. Seeley

- Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM)

Publisher Correction: GLP-1R–GIPR–PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice | Nature